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AOD-9604 has a method of action that does not suppress appetite or absorption of food

This substitution may potentially increase the resistance of the peptide to enzymatic degradation and improve its stability

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As of June 2026, the FDA's December 2024 Pharmacy Compounding Advisory Committee evaluation concluded that the criteria weighed against placing AOD-9604 (free base) or AOD-9604 acetate on the 503A Bulks List, and AOD-9604 is currently listed as Nominated but Withdrawn from FDA Category 2